Ts’ilʔos Park is located in a relatively undeveloped and isolated part of the Chilcotin. As the crow flies, the park is approximately 160km southwest of Williams Lake, or 250km north of Vancouver. There are two main vehicle access routes into the park, and two campgrounds, one at the end of each route. Both routes take four to six hours from Williams Lake, though travel time varies considerably depending on weather conditions. Roads are rough, and conditions vary considerably. Drive carefully and with lights on. The nearest communities to the park are Nemiah Valley, Hanceville, Tatla Lake and Williams Lake.
No scheduled flights serve the park. Several airstrips are located outside the park boundary; a Park Use Permit is required for commercial air access within the park.
Topographical map numbers 1:50,000 92N/1, 92N/8, 92O/4, 92O/5, 92N/9, 92J/13 and 92K/16 cover the park. These are necessary for hikers, horseback riders and other backcountry travellers.